The NBAF Complex: A Potential Drug Target and Biomarker (P25018)

Target Name: nBAF complex

NCBI ID: P25018

nBAF complex

Other Name(s): None

The NBAF Complex: A Potential Drug Target and Biomarker

The NBAF complex, also known as the nuclear factor of activating transcription factor Nrf2, is a protein that plays a crucial role in the regulation of gene expression and DNA damage repair. It is a key player in the cellular response to environmental stressors, including those caused by exposure to harmful radiation, chemicals, and radiation-induced mutations. The NBAF complex is also a potential drug target and biomarker for a variety of diseases, including cancer.

The NBAF complex is composed of several subunits that are involved in the regulation of DNA replication, transcription, and repair. The most well-studied subunit is the Nrf2 protein, which is a transcription factor that plays a central role in the regulation of gene expression. Nrf2 is a key component of the NBAF complex and is responsible for activating target genes that are exposed to DNA damage.

The NBAF complex is also involved in the regulation of the cellular response to environmental stressors. Many of these stressors can cause DNA damage, which can lead to the activation of the NBAF complex and the expression of its subunits. For example, exposure to radiation can cause DNA damage and the activation of the NBAF complex, leading to the transcription of genes involved in DNA repair and stress response.

The NBAF complex is also involved in the regulation of cell cycle progression. It plays a role in the G1 phase of the cell cycle, which is responsible for cell growth and preparation for cell division. During this phase, the NBAF complex is involved in the regulation of the expression of genes involved in cell cycle progression and the maintenance of the integrity of the cell membrane.

The NBAF complex is also involved in the regulation of cellular signaling pathways. It plays a role in several signaling pathways that are involved in the regulation of cellular processes, including cell growth, differentiation, and stress response. The NBAF complex is also involved in the regulation of the signaling pathway that is responsible for the regulation of cell survival and proliferation, known as the apoptosis signaling pathway.

The NBAF complex is a potential drug target for a variety of diseases. Its involvement in the regulation of cellular processes that are involved in the development and progression of many diseases makes it an attractive target for intervention. For example, the NBAF complex has been implicated in the development of cancer, and there is evidence to suggest that inhibiting the activity of the NBAF complex may be an effective way to treat cancer.

The NBAF complex is also a potential biomarker for a variety of diseases. Its involvement in the regulation of cellular processes that are involved in the development and progression of many diseases makes it an attractive target for diagnostic tools. For example, the NBAF complex has been shown to be involved in the regulation of the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

In conclusion, the NBAF complex is a protein that plays a crucial role in the regulation of gene expression and DNA damage repair. Its involvement in the cellular response to environmental stressors and its involvement in the regulation of cellular processes that are involved in the development and progression of many diseases make it an attractive target for intervention and diagnostic tools. Further research is needed to fully understand the role of the NBAF complex in the regulation of cellular processes and its potential as a drug target and biomarker.

Protein Name: NBAF Complex

The "nBAF complex Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about nBAF complex comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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